2-Chlorobenzenesulfonyl chloride → 8-(2-Chlorophenylsulfonyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione

반응식

[Cl:24][c:25]1[c:26]([S:31](=[O:32])(=[O:33])[Cl:34])[cH:27][cH:28][cH:29][cH:30]1.[F:1][C:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[NH:17][CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]>>[F:1][C:2]([CH2:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[N:17]([S:31]([c:26]2[c:25]([Cl:24])[cH:30][cH:29][cH:28][cH:27]2)(=[O:32])=[O:33])[CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]

참가 물질

반응물 2

HCID 761872-Chlorobenzenesulfonyl chloride

HCID 584784152-(4-(2,2,2-Trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione

생성물 1

HCID 534826868-(2-Chlorophenylsulfonyl)-2-(4-(2,2,2-trifluoroethyl)phenyl)-2,8-diazaspiro[4.5]decane-1,7-dione

출처 및 근거

ORD 기록: ord-59abaa16a406470c996be3596d3628b9
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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