2-(3-Bromopropoxy)tetrahydro-2H-pyran → 5-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine

HRID 1220752노트

반응식

HRID 1220752 반응식
[Br:28][CH2:29][CH2:30][CH2:31][O:32][CH:33]1[O:34][CH2:35][CH2:36][CH2:37][CH2:38]1.[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]2-[c:15]2[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]2)[nH:25][n:26][cH:27]3)[n:8]1>>[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]2-[c:15]2[cH:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][cH:19][cH:20]2)[n:25][n:26]([CH2:29][CH2:30][CH2:31][O:32][CH:33]2[O:34][CH2:35][CH2:36][CH2:37][CH2:38]2)[cH:27]3)[n:8]1

참가 물질

3

반응물 2

HCID 27779882-(3-Bromopropoxy)tetrahydro-2H-pyranHCID 670138695-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine

생성물 1

HCID 670145475-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine

출처 및 근거

ORD 기록
ord-04e0df9ac3f44a5c87ed2cab7cff0f47
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

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