alpha-Naphthyl isocyanate → 6-Arylpyrido[2,3-d]pyrimidine deriv. 70

반응식

[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:17][CH2:18][CH2:19][CH2:20][N:21]4[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]4)[n:15][cH:16]3)[n:28][c:29]2[NH2:30])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[c:31]1([N:41]=[C:42]=[O:43])[cH:32][cH:33][cH:34][c:35]2[cH:36][cH:37][cH:38][cH:39][c:40]12>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:17][CH2:18][CH2:19][CH2:20][N:21]4[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]4)[n:15][cH:16]3)[n:28][c:29]2[NH:30][C:42]([NH:41][c:31]2[cH:32][cH:33][cH:34][c:35]3[cH:36][cH:37][cH:38][cH:39][c:40]23)=[O:43])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

참가 물질

반응물 2

HCID 66589alpha-Naphthyl isocyanate

HCID 53281486-(2,6-dichlorophenyl)-2-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidine-2,7-diamine

생성물 1

HCID 53281726-Arylpyrido[2,3-d]pyrimidine deriv. 70

출처 및 근거

ORD 기록: ord-70e825cf25d7474abda929d2295b7c4b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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