{3-Methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol → {5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol

반응식

[CH3:1][c:2]1[cH:3][c:4](-[c:5]2[cH:6][cH:7][c:8]([O:9][C:10]([F:11])([F:12])[F:13])[cH:14][cH:15]2)[s:16][c:17]1[CH2:18][OH:19].[F:20][c:21]1[c:22](-[c:31]2[cH:32][c:33]([CH3:48])[c:34]([CH2:36][O:37][Si:38]([CH:39]([CH3:40])[CH3:41])([CH:42]([CH3:43])[CH3:44])[CH:45]([CH3:46])[CH3:47])[s:35]2)[cH:23][cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1>>[F:20][c:21]1[c:22](-[c:31]2[cH:32][c:33]([CH3:48])[c:34]([CH2:36][OH:37])[s:35]2)[cH:23][cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1

참가 물질

반응물 2

HCID 21986356{3-Methyl-5-[4-(trifluoromethoxy)phenyl]thien-2-yl}methanol

HCID 69591680({5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)(triisopropyl)silane

생성물 1

HCID 21986424{5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol

출처 및 근거

ORD 기록: ord-0b8c95f6cd5c48d7b583d837951694d2
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…