4-Bromo-2-methylthiophene → 5-(5-Methyl-thiophen-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

반응식

[Br:26][c:27]1[cH:28][c:29]([CH3:32])[s:30][cH:31]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([B:17]3[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]3)[cH:14][c:15]2[CH2:16]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13](-[c:27]3[cH:28][c:29]([CH3:32])[s:30][cH:31]3)[cH:14][c:15]2[CH2:16]1

참가 물질

반응물 2

HCID 6385844-Bromo-2-methylthiophene

HCID 16102684Tert-butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)isoindoline-2-carboxylate

생성물 1

HCID 577534645-(5-Methyl-thiophen-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-7c9eb92bbc6f4b1aa3c0c446c33313a8
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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