3,5-Difluorobenzaldehyde → tert-Butyl 1-(3,5-difluorobenzyl)piperidin-4-ylcarbamate

반응식

[F:15][c:16]1[cH:17][c:18]([CH:19]=[O:20])[cH:21][c:22]([F:24])[cH:23]1.[NH:1]1[CH2:2][CH2:3][CH:4]([NH:7][C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:5][CH2:6]1>>[N:1]1([CH2:19][c:18]2[cH:17][c:16]([F:15])[cH:23][c:22]([F:24])[cH:21]2)[CH2:2][CH2:3][CH:4]([NH:7][C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:5][CH2:6]1

참가 물질

반응물 2

HCID 5881603,5-Difluorobenzaldehyde

HCID 7238334-(N-Boc-amino)piperidine

생성물 1

HCID 22182435tert-Butyl 1-(3,5-difluorobenzyl)piperidin-4-ylcarbamate

출처 및 근거

ORD 기록: ord-243c7f55bafb4871a5543c41535f8e68
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…