5-Methoxy-2-methyl-1H-benzo[d]imidazole-6-carbaldehyde → [6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(6-methoxy-2-methyl-3H-benzoimidazol-5-yl)-methanone

반응식

[Br:15][c:16]1[cH:17][cH:18][c:19]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([F:29])[cH:27][cH:28]2)[n:20][cH:21]1.[CH3:1][O:2][c:3]1[c:4]([CH:13]=[O:14])[cH:5][c:6]2[c:7]([n:8][c:9]([CH3:11])[nH:10]2)[cH:12]1>>[CH3:1][O:2][c:3]1[c:4]([C:13](=[O:14])[c:16]2[cH:17][cH:18][c:19]([NH:22][c:23]3[c:24]([F:30])[cH:25][c:26]([F:29])[cH:27][cH:28]3)[n:20][cH:21]2)[cH:5][c:6]2[c:7]([n:8][c:9]([CH3:11])[nH:10]2)[cH:12]1

참가 물질

반응물 2

HCID 150555405-Methoxy-2-methyl-1H-benzo[d]imidazole-6-carbaldehyde

HCID 22349574(5-Bromo-pyridin-2-yl)-(2,4-difluoro-phenyl)-amine

생성물 1

HCID 10111212[6-(2,4-Difluoro-phenylamino)-pyridin-3-yl]-(6-methoxy-2-methyl-3H-benzoimidazol-5-yl)-methanone

출처 및 근거

ORD 기록: ord-603c6b8059d54c088c3d00bf04abfe85
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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