Dichloromethane → 3-Amino-5-benzoyl-1-methyl-3,4-dihydro-1,5-benzodiazepin-2-one

반응식

[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][N:10]([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[c:11]2[c:12]([cH:17][cH:18][cH:19][cH:20]2)[N:13]([CH3:16])[C:14]1=[O:15])([CH3:5])([CH3:6])[CH3:29].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH2:7][CH:8]1[CH2:9][N:10]([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[c:11]2[c:12]([cH:17][cH:18][cH:19][cH:20]2)[N:13]([CH3:16])[C:14]1=[O:15]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 69284319tert-butyl N-(5-benzoyl-1-methyl-2-oxo-3,4-dihydro-1,5-benzodiazepin-3-yl)carbamate

생성물 1

HCID 210765923-Amino-5-benzoyl-1-methyl-3,4-dihydro-1,5-benzodiazepin-2-one

출처 및 근거

ORD 기록: ord-8e07a158588e49dea0633abc5668cb39
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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