Toluene → 6-(2,5-Difluorophenyl)nicotinic acid

HRID 123159노트

반응식

[CH3:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[Cl:36][CH2:37][Cl:38].[F:1][c:2]1[c:3](-[c:9]2[n:10][cH:11][c:12]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[cH:20][cH:21]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28]>>[F:1][c:2]1[c:3](-[c:9]2[n:10][cH:11][c:12]([C:13](=[O:14])[OH:15])[cH:20][cH:21]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1