2-(4,6-Dimethoxy-5-nitropyrimidin-2-yl)-6-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline → 4,6-dimethoxy-2-(6-(trifluoromethyl)-3,4-dihydroisoquinolin-2(1H)-yl)pyrimidin-5-amine

반응식

[CH3:1][O:2][c:3]1[n:4][c:5]([N:14]2[CH2:15][c:16]3[cH:17][cH:18][c:19]([C:24]([F:25])([F:26])[F:27])[cH:20][c:21]3[CH2:22][CH2:23]2)[n:6][c:7]([O:12][CH3:13])[c:8]1[N+:9]([O-:10])=[O:11].[H:28][H:29]>>[CH3:1][O:2][c:3]1[n:4][c:5]([N:14]2[CH2:15][c:16]3[cH:17][cH:18][c:19]([C:24]([F:25])([F:26])[F:27])[cH:20][c:21]3[CH2:22][CH2:23]2)[n:6][c:7]([O:12][CH3:13])[c:8]1[NH2:9]

참가 물질

반응물 2

HCID 598687862-(4,6-Dimethoxy-5-nitropyrimidin-2-yl)-6-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline

HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 598687824,6-dimethoxy-2-(6-(trifluoromethyl)-3,4-dihydroisoquinolin-2(1H)-yl)pyrimidin-5-amine

출처 및 근거

ORD 기록: ord-4414fde3894e402985ac863e89befdd8
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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