Dichloromethane → 3-[4-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-1-(oxan-2-yl)pyrazolo[5,4-d]pyrimidin-3-yl]prop-2-ynyl methanesulfonate

반응식

[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][S:42]([Cl:43])(=[O:44])=[O:45].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH3:33])[c:6]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[c:15]4[c:16]([n:17][cH:18][n:19]3)[n:20]([CH:27]3[O:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[n:21][c:22]4[C:23]#[C:24][CH2:25][OH:26])[CH2:12][CH2:13]2)[cH:7]1.[Cl:46][CH2:47][Cl:48]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH3:33])[c:6]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[c:15]4[c:16]([n:17][cH:18][n:19]3)[n:20]([CH:27]3[O:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[n:21][c:22]4[C:23]#[C:24][CH2:25][O:26][S:42]([CH3:41])(=[O:44])=[O:45])[CH2:12][CH2:13]2)[cH:7]1