Methanol → tert-Butyl 4-(4-bromo-1-(2-hydroxyethyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15]([CH2:20][CH2:21][O:22][CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][O:28]3)[cH:16][c:17]([Br:19])[n:18]2)[CH2:12][CH2:13]1.[CH3:40][OH:41].[c:29]1([CH3:30])[cH:31][cH:32][c:33]([S:34]([OH:35])(=[O:36])=[O:37])[cH:38][cH:39]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15]([CH2:20][CH2:21][OH:22])[cH:16][c:17]([Br:19])[n:18]2)[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 887Methanol

HCID 6101p-Toluenesulfonic acid

HCID 67265112tert-Butyl 4-(4-bromo-1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

생성물 1

HCID 67265139tert-Butyl 4-(4-bromo-1-(2-hydroxyethyl)-1H-imidazol-2-yl)piperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-71c7fc6217ef412691ae70332efe0012
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

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