Chlorotrimethylsilane → N-(4-(4-(3-aminosulfonyl-phenylamino)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)phenyl)-N-methylacetamide

HRID 1240333노트

반응식

[CH3:44][Si:45]([Cl:46])([CH3:47])[CH3:48].[Cl:1][c:2]1[n:3][c:4]([NH:21][c:22]2[cH:23][c:24]([S:28](=[O:29])(=[O:30])[NH2:31])[cH:25][cH:26][cH:27]2)[c:5]2[c:6]([n:7]1)[n:8]([S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([CH3:18])[cH:19][cH:20]1)[cH:9][cH:10]2.[NH2:32][c:33]1[cH:34][cH:35][c:36]([N:39]([C:40]([CH3:41])=[O:42])[CH3:43])[cH:37][cH:38]1.[O:49]1[CH2:50][CH2:51][O:52][CH2:53][CH2:54]1>>[c:2]1([NH:32][c:33]2[cH:34][cH:35][c:36]([N:39]([C:40]([CH3:41])=[O:42])[CH3:43])[cH:37][cH:38]2)[n:3][c:4]([NH:21][c:22]2[cH:23][c:24]([S:28](=[O:29])(=[O:30])[NH2:31])[cH:25][cH:26][cH:27]2)[c:5]2[c:6]([n:7]1)[n:8]([S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([CH3:18])[cH:19][cH:20]1)[cH:9][cH:10]2