Ethylamine → N-Ethyl-3-nitropyridin-4-amine

HRID 1241970노트

반응식

Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[CH2:11]([NH2:13])[CH3:12]>>[CH2:11]([NH:13][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9])[CH3:12]

참가 물질

반응물 2

HCID 6341Ethylamine

HCID 27357814-Chloro-3-nitropyridine

생성물 1

HCID 21937597N-Ethyl-3-nitropyridin-4-amine

실험 절차

In a manner similar to example 31, the title compound was prepared from 4-chloro-3-nitropyridine, prepared according to published procedure [J. Med. Chem. 1996, 39, 487–493], and ethylamine. 1H-NMR (CDCl3): δ 9.22 (1H, s), 8.30 (1H, d), 8.10 (1H, br s), 6.71 (1H, d), 3.40 (2H, m), 1.39 (3H, t).

후처리

customprepared

출처 및 근거

ORD 기록: ord-9f0af2f569834325bb25c4cc9e1790a3
출처 데이터셋: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07115640B2

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