HCID 21062816, 화합물 → HCID 21062607, 화합물

HRID 1242793노트

반응식

HRID 1242793 반응식
C(N1CCN([NH:14][C:15](=[O:23])[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)CC1)(OC(C)(C)C)=O.[CH2:24]([C:26]1[N:31]=[C:30]([N:32]2[CH2:37][CH2:36]N(C(OC(C)(C)C)=O)[CH2:34][CH2:33]2)[C:29]2[CH:45]=[C:46]([CH2:48][CH3:49])[S:47][C:28]=2[N:27]=1)[CH3:25]>>[CH2:24]([C:26]1[N:31]=[C:30]([N:32]2[CH2:37][CH2:36][N:14]([C:15](=[O:23])[CH2:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:34][CH2:33]2)[C:29]2[CH:45]=[C:46]([CH2:48][CH3:49])[S:47][C:28]=2[N:27]=1)[CH3:25]

참가 물질

3

반응물 2

HCID 21062816HCID 21062816, 화합물HCID 21939585HCID 21939585, 화합물

생성물 1

HCID 21062607HCID 21062607, 화합물수율 27%

실험 절차

Phenylacetamidopiperazine hydrochloride (Example 141) was reacted 2-ethyl-4-chloro-6-ethylthienopyrimidine (Example 156) according to Example 87. Yield=27%, ES-MS: (M+H)+ 395.

출처 및 근거

ORD 기록
ord-4c1430bfd51b4ad28fda2be2e7a4af3a
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07115741B2

반응 노트

불러오는 중…