HCID 21062852, 화합물 → HCID 21062619, 화합물

HRID 1242794노트

반응식

HRID 1242794 반응식
C(N1CCN([NH:14][C:15](=[O:23])[CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)CC1)(OC(C)(C)C)=O.[CH2:24]([C:26]1[S:34][C:33]2[N:32]=[C:31]([CH2:35][CH2:36][CH3:37])[N:30]=[C:29]([N:38]3[CH2:43][CH2:42]N(C(OC(C)(C)C)=O)[CH2:40][CH2:39]3)[C:28]=2[CH:27]=1)[CH3:25]>>[CH2:24]([C:26]1[S:34][C:33]2[N:32]=[C:31]([CH2:35][CH2:36][CH3:37])[N:30]=[C:29]([N:38]3[CH2:43][CH2:42][N:14]([C:15](=[O:23])[CH2:16][C:17]4[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=4)[CH2:40][CH2:39]3)[C:28]=2[CH:27]=1)[CH3:25]

참가 물질

3

반응물 2

HCID 21062852HCID 21062852, 화합물HCID 21939585HCID 21939585, 화합물

생성물 1

HCID 21062619HCID 21062619, 화합물수율 36%

실험 절차

Phenylacetamidopiperazine hydrochloride (Example 141) was reacted 2-propyl-4-chloro-6-ethylthienopyrimidine (Example 159) according to Example 87. Yield 36%, ES-MS: (M+H)+ 409.

출처 및 근거

ORD 기록
ord-709d684d8c3e483cb77a3e4e904481d2
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07115741B2

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