참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Thiourea | HCID 2723790 | — |
| 반응물 | (E)-1-(4-chlorophenyl)-3-(dimethylamino)prop-2-en-1-one | HCID 5375260 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 178527862 | HCID 178527862 | — |
반응 단계
To a solution of (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one (1.5 g, 7.2 mmol) in ethanol (25 ml) was added thiourea (0.60 g, 7.9 mmol) and potassium carbonate (K2CO3) (1.19 g. 8.63 mmol). The resulting suspension was heated to 85° C. for 12 hours then cooled to ambient temperature. The resulting solid was collected and thoroughly washed with water and hexanes to provide a beige solid: EI-MS (m/z) 222 [M+1]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07122544B2 |
|---|
| 출처 데이터셋 | uspto-grants-2006_10 |
|---|
| ORD ID | ord-7466dac3b45341168ec0e634a3e6fcb6 |
|---|
| 출처 메모 | uspto-grants-2006_10 |
|---|
