2,2-Dimethylsuccinimide → HCID 10476765, 화합물

HRID 1245312노트

반응식

HRID 1245312 반응식
[CH3:1][C:2]1([CH3:9])[CH2:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[CH2:10]([C:13]1[C:21]2[O:20][N:19]=[C:18]([C:22]([F:25])([F:24])[F:23])[C:17]=2[CH:16]=[CH:15][C:14]=1[O:26][CH2:27][CH2:28][CH2:29]Br)[CH2:11][CH3:12]>>[CH3:1][C:2]1([CH3:9])[CH2:6][C:5](=[O:7])[N:4]([CH2:29][CH2:28][CH2:27][O:26][C:14]2[CH:15]=[CH:16][C:17]3[C:18]([C:22]([F:24])([F:25])[F:23])=[N:19][O:20][C:21]=3[C:13]=2[CH2:10][CH2:11][CH3:12])[C:3]1=[O:8]

참가 물질

3

반응물 2

HCID 2256782,2-DimethylsuccinimideHCID 120312593-Trifluoromethyl-7-propyl-6-(3-bromopropyloxy)-benzisoxazole

생성물 1

HCID 10476765HCID 10476765, 화합물

실험 절차

3,3-Dimethyl-1-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)pyrrolidine-2,5-dione was prepared as for Example 10 from 3,3-dimethylpyrrolidine-2,5-dione and the bromide from Example 7. After aqueous work-up and silica gel chromatography, the title compound was obtained.

출처 및 근거

ORD 기록
ord-8a45f17e9063429997400d4d0f983f64
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07125865B2

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