5-Bromopentanoate → HCID 21910985, 화합물

반응식

Br[CH2:2][CH2:3][CH2:4][CH2:5][C:6]([O-:8])=[O:7].[CH3:9][C:10]1([CH3:43])[N:14](CCCC(O)=O)[C:13](=[O:21])[N:12]([CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH:38]=[CH:37][C:29]3[C:30]([C:33]([F:36])([F:35])[F:34])=[N:31][O:32][C:28]=3[C:27]=2[CH2:39][CH2:40][CH3:41])[C:11]1=[O:42]>>[CH3:43][C:10]1([CH3:9])[N:14]([CH:3]([CH3:2])[CH2:4][CH2:5][C:6]([OH:8])=[O:7])[C:13](=[O:21])[N:12]([CH2:22][CH2:23][CH2:24][O:25][C:26]2[CH:38]=[CH:37][C:29]3[C:30]([C:33]([F:36])([F:35])[F:34])=[N:31][O:32][C:28]=3[C:27]=2[CH2:39][CH2:40][CH3:41])[C:11]1=[O:42]

참가 물질

반응물 2

HCID 69941705-Bromopentanoate

HCID 21911042HCID 21911042, 화합물

생성물 1

HCID 21910985HCID 21910985, 화합물

실험 절차

4-[5,5-Dimethyl-2,4-dioxo-3-(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)imidazolidin-1-yl]pentanoic acid was prepared as for Example 37, substituting 5-bromovalerate for the 4-bromobutyrate of Example 37.

출처 및 근거

ORD 기록: ord-2b5db0ec044c4aa18ffc935546940103
출처 데이터셋: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07125865B2

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