Piperidine → HCID 21912775, 화합물

반응식

C(OC([N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[N:18]([CH2:19][CH3:20])[N:17]=[C:16]([CH2:21][O:22][CH3:23])[C:15]=2[CH3:24])[CH2:10][CH2:9]1)=O)(C)(C)C.N1CCCCC1>>[CH2:19]([N:18]1[C:14]([CH:11]2[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]2)=[C:15]([CH3:24])[C:16]([CH2:21][O:22][CH3:23])=[N:17]1)[CH3:20]

참가 물질

반응물 2

HCID 8082Piperidine

HCID 21912762HCID 21912762, 화합물

생성물 1

HCID 21912775HCID 21912775, 화합물

실험 절차

The title compound was prepared from 1-(tert-butoxycarbonyl)-4-(1-ethyl-3-methoxymethyl-4-methyl-(1H)-pyrazol-5-yl)piperidine (from Step A) using a procedure analogous to that described for Piperidine 8, Step F. 1H-NMR (500 MHz) δ 1.36 (t, J=7.2, 3H), 1.71–1.74 (m, 2H), 1.97–2.09 (m, 2H), 2.11 (s, 3H), 2.72–2.80 (m, 3H), 3.25–3.35 (m, 2H), 3.37 (s, 3H), 4.11 (q, J=7.2, 2H), 4.37 (s, 2H).

출처 및 근거

ORD 기록: ord-bdb10a67c4684789a54cf0050433c79c
출처 데이터셋: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07125887B2

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