3-Chloro-2-methylbenzenesulfonyl chloride → N-(4-Butyl-1,3-thiazol-2-yl)-3-chloro-2-methylbenzenesulfonamide

HRID 1245639

반응식

HRID 1245639 반응식
[CH2:1]([C:5]1[N:6]=[C:7]([NH2:10])[S:8][CH:9]=1)[CH2:2][CH2:3][CH3:4].[Cl:11][C:12]1[C:13]([CH3:22])=[C:14]([S:18](Cl)(=[O:20])=[O:19])[CH:15]=[CH:16][CH:17]=1>>[CH2:1]([C:5]1[N:6]=[C:7]([NH:10][S:18]([C:14]2[CH:15]=[CH:16][CH:17]=[C:12]([Cl:11])[C:13]=2[CH3:22])(=[O:19])=[O:20])[S:8][CH:9]=1)[CH2:2][CH2:3][CH3:4]

참가 물질

3

반응물 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 104871244-Butyl-1,3-thiazol-2-amine

생성물 1

HCID 10269058N-(4-Butyl-1,3-thiazol-2-yl)-3-chloro-2-methylbenzenesulfonamide수율 22%

실험 절차

The title compound was prepared from 4-butyl-1,3-thiazol-2-ylamine (METHOD H) and 3-chloro-2-methylbenzenesulfonyl chloride according to METHOD A, yellow solid, 52 mg (22% yield): HRMS Calcd (found) for C14H17ClN2O2S2 m/z 344.0420 (334.0414).

출처 및 근거

ORD 기록
ord-91d9d7edf35e4796917fccc7089b170c
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07125900B2

연결된 노트

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