Acetonitrile → HCID 178470380, 화합물

HRID 12468

반응식

HRID 12468 반응식
[CH2:1]([O:3][C:4](=[O:10])[C:5](=O)[C:6](=O)[CH3:7])[CH3:2].[C:11]1([CH2:21][NH2:22])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1.C(#[N:25])C>>[CH2:1]([O:3][C:4]([C:5]1[NH:22][C:21]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)=[N:25][C:6]=1[CH3:7])=[O:10])[CH3:2]

참가 물질

4

반응물 3

HCID 6342AcetonitrileHCID 83551-NaphthalenemethanamineHCID 12260829Ethyl 2,3-dioxobutanoate

생성물 1

HCID 178470380HCID 178470380, 화합물

실험 절차

A solution of 2,3-dioxobutyric acid ethyl ester, (Z)-2-oxime (3 g), 1-naphthalenemethylamine (3.26 g) in acetonitrile (45 ml) is refluxed for 10 hr to give a white precipitate. The solid is then collected, washed with acetonitrile and dried to yield 5-methyl-2-naphthalen-1-yl-3H-imidazole-4-carboxylic acid ethyl ester. LCMS 281.3 (M+1).

후처리

  1. customto give a white precipitate
  2. customThe solid is then collected
  3. washwashed with acetonitrile
  4. customdried

출처 및 근거

ORD 기록
ord-3f58c3e8254649fcb1cc5fa9783b5209
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728009B1

연결된 노트

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