4-(Aminomethyl)benzonitrile → HCID 21905122, 화합물

HRID 1247248노트

반응식

HRID 1247248 반응식
[F:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH:10]([O:14][CH3:15])[C:11]([OH:13])=O.[NH2:16][CH2:17][C:18]1[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][CH:19]=1>>[C:17]([C:18]1[CH:25]=[CH:24][C:21]([CH2:22][NH:23][C:11](=[O:13])[CH:10]([C:3]2[CH:4]=[CH:5][C:6]([O:8][CH3:9])=[CH:7][C:2]=2[F:1])[O:14][CH3:15])=[CH:20][CH:19]=1)#[N:16]

참가 물질

3

반응물 2

HCID 826084-(Aminomethyl)benzonitrileHCID 67373142(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid

생성물 1

HCID 21905122HCID 21905122, 화합물

실험 절차

(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid was coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide. Colorless oil. MS 329.2 ([M+H]+)

출처 및 근거

ORD 기록
ord-1db63373691c4c889397afa42b9ee21a
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07129238B2

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