4-(Aminomethyl)benzonitrile → HCID 21905227, 화합물

반응식

[OH:1][C:2]1[CH:3]=[C:4]([CH:8]([O:12][CH3:13])[C:9]([OH:11])=O)[CH:5]=[CH:6][CH:7]=1.[NH2:14][CH2:15][C:16]1[CH:23]=[CH:22][C:19]([C:20]#[N:21])=[CH:18][CH:17]=1>>[C:15]([C:16]1[CH:23]=[CH:22][C:19]([CH2:20][NH:21][C:9](=[O:11])[CH:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([OH:1])[CH:3]=2)[O:12][CH3:13])=[CH:18][CH:17]=1)#[N:14]

참가 물질

반응물 2

HCID 826084-(Aminomethyl)benzonitrile

HCID 69289011HCID 69289011, 화합물

생성물 1

HCID 21905227HCID 21905227, 화합물

실험 절차

(RS)-(3-Hydroxy-phenyl)-methoxy-acetic acid was coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-(3-hydroxy-phenyl)-2-methoxy-acetamide. Colorless oil.

출처 및 근거

ORD 기록: ord-45118c8c36fe4f66a6d5805800668c06
출처 데이터셋: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07129238B2

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