HCID 21905227, 화합물 → HCID 21905173, 화합물
반응식
[C:1]([C:3]1[CH:22]=[CH:21][C:6]([CH2:7][NH:8][C:9](=[O:20])[CH:10]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([OH:19])[CH:14]=2)[O:11][CH3:12])=[CH:5][CH:4]=1)#[N:2].I[CH:24]([CH3:26])[CH3:25].C(=O)([O-])[O-].[Cs+].[Cs+]>CN(C=O)C>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([CH2:7][NH:8][C:9](=[O:20])[CH:10]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH:24]([CH3:26])[CH3:25])[CH:14]=2)[O:11][CH3:12])=[CH:21][CH:22]=1)#[N:2]참가 물질
4
실험 절차
In analogy to example 16.4, (RS)-N-(4-cyano-benzyl)-2-(3-hydroxy-phenyl)-2-methoxy-acetamide was alkylated with 2-iodopropane/cesium carbonate in DMF to give (RS)-N-(4-cyano-benzyl)-2-(3-isopropoxy-phenyl)-2-methoxy-acetamide as a colorless oil. MS 339.2 ([M+H]+)
출처 및 근거
- ORD 기록
- ord-9c6514a685fc415ebefa616b879d6793