Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Aminomethyl)-3-fluorobenzonitrile → (RS)-N-(4-cyano-2-fluoro-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Aminomethyl)-3-fluorobenzonitrile | HCID 21905443 | — |
| 반응물 | (RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid | HCID 67373142 | — |
| 생성물 | (RS)-N-(4-cyano-2-fluoro-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide | HCID 21905701 | — |
반응 단계
(RS)-(2-Fluoro-4-methoxy-phenyl)-methoxy-acetic acid (example 15.1) was coupled with 4-aminomethyl-3-fluoro-benzonitrile according to general procedure B to give (RS)-N-(4-cyano-2-fluoro-benzyl)-2-(2-fluoro-4-methoxy-phenyl)-2-methoxy-acetamide. Yellow oil. MS 347.3 ([M+H]+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07129238B2 |
| 출처 데이터셋 | uspto-grants-2006_10 |
| ORD ID | ord-c4db54b73cf84257909fd503c543c6d8 |
| 출처 메모 | uspto-grants-2006_10 |