4-(Aminomethyl)benzonitrile → HCID 21905225, 화합물

HRID 1247307노트

반응식

HRID 1247307 반응식
[CH3:1][O:2][C:3]([C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][CH:9]=1)([CH3:7])[C:4]([OH:6])=O.[NH2:18][CH2:19][C:20]1[CH:27]=[CH:26][C:23]([C:24]#[N:25])=[CH:22][CH:21]=1>>[C:19]([C:20]1[CH:27]=[CH:26][C:23]([CH2:24][NH:25][C:4](=[O:6])[C:3]([O:2][CH3:1])([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH:11]=[CH:10][CH:9]=2)[CH3:7])=[CH:22][CH:21]=1)#[N:18]

참가 물질

3

반응물 2

HCID 826084-(Aminomethyl)benzonitrileHCID 112184702-Methoxy-2-(1-naphthyl)propionic Acid

생성물 1

HCID 21905225HCID 21905225, 화합물

실험 절차

2-Methoxy-2-(1-naphtyl)propionic acid was coupled with 4-aminomethyl benzonitrile according to general procedure B to give (RS)-N-(4-cyano-benzyl)-2-methoxy-2-naphthalen-1-yl-propionamide. Colorless foam. MS 345.2 ([M+H]+)

출처 및 근거

ORD 기록
ord-5660ae0fe4ba42faada45eb7af6a2016
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07129238B2

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