Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Aminomethyl)-3-chlorobenzonitrile → (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Aminomethyl)-3-chlorobenzonitrile | HCID 4089788 | — |
| 반응물 | (RS)-(2,6-Difluoro-4-methoxy-phenyl)-ethoxy-acetic acid | HCID 21905754 | — |
| 생성물 | (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide | HCID 21905488 | — |
반응 단계
(RS)-(2,6-Difluoro-4-methoxy-phenyl)-ethoxy-acetic acid was coupled with 4-aminomethyl-3-chlorobenzonitrile (CAS 202521-97-9) according to general procedure C to give (RS)-N-(2-chloro-4-cyano-benzyl)-2-(2,6-difluoro-4-methoxy-phenyl)-2-ethoxy-acetamide. Colorless oil. MS 395.0 ([M+H]+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07129238B2 |
| 출처 데이터셋 | uspto-grants-2006_10 |
| ORD ID | ord-900b769329394c4f8fc1a4bf56a2a211 |
| 출처 메모 | uspto-grants-2006_10 |