Sulfuric Acid → 1H-Pyrazole, 4,5-diamine-1-methyl-, sulfate (1:1)

HRID 1247771

반응식

HRID 1247771 반응식
[NH2:1][C:2]1[N:6]([CH3:7])[N:5]=[CH:4][C:3]=1[N:8]=O.[S:10](=[O:14])(=[O:13])([OH:12])[OH:11]>O.[Pd]>[S:10](=[O:12])(=[O:11])([OH:14])[OH:13].[NH2:8][C:3]1[CH:4]=[N:5][N:6]([CH3:7])[C:2]=1[NH2:1]

참가 물질

5

반응물 2

HCID 1118Sulfuric AcidHCID 128515805-Amino-1-methyl-4-nitrosopyrazole

생성물 1

HCID 219045711H-Pyrazole, 4,5-diamine-1-methyl-, sulfate (1:1)

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 962Water용매

실험 절차

To a solution of 5-amino-1-methyl-4-nitrosopyrazole (1 g) in water (40 ml) were added concentrated sulfuric acid (0.423 ml) and palladium on carbon (0.3 g) under a hydrogen atmosphere. The mixture was stirred overnight. The reaction mixture was filtered, and the filtrate was evaporated in vacuo. To the residue was added isopropyl alcohol, and the resulting precipitate was collected by filtration to give 4,5-diamino-1-methylpyrazole sulfuric acid salt (1.71 g).

후처리

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated in vacuo
  3. additionTo the residue was added isopropyl alcohol
  4. filtrationthe resulting precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-d95b855a751240af91eca2fb50ef3e16
출처 데이터셋
uspto-grants-2006_10
특허 번호
US07129232B2

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