Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Isoamyl Nitrite | HCID 8053 | — |
| 반응물 | 2-(5-amino-1H-pyrazol-1-yl)ethan-1-ol | HCID 320281 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso- | HCID 10149014 | 51.3% |
반응 단계
To a solution of 5-amino-1-(2-hydroxyethyl)pyrazole (6.35 g) in a mixed solvent of ethanol (25 ml) and concentrated hydrochloric acid (0.035 ml) was added dropwise isoamyl nitrite (7.03 g). The mixture was stirred at room temperature for 17 hours. The crystalline residue was collected by filtration and dried in vacuo to give 5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole (4.0 g) as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07129232B2 |
| 출처 데이터셋 | uspto-grants-2006_10 |
| ORD ID | ord-caef93d0f1284e4084569b09d22d8d2d |
| 출처 메모 | uspto-grants-2006_10 |