Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso- | HCID 10149014 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4,5-Diamino-1-(2-hydroxyethyl)pyrazole sulfate | HCID 11673148 | — |
반응 단계
A solution of 5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole (97 g) in a mixed solvent of sulfuric acid (34 ml) and water (2000 ml) was treated with 10% palladium on carbon (10 g) under a hydrogen atmosphere at room temperature for 4 days. After the catalyst was filtered off, the filtrate was concentrated in vacuo. The residue was triturated with methanol and dried in vacuo to give 4,5-diamino-1-(2-hydroxyethyl)pyrazole sulfuric acid salt (90.2 g) as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07129232B2 |
| 출처 데이터셋 | uspto-grants-2006_10 |
| ORD ID | ord-bf3e239bfe704c928fd15c7ee1f8a9f2 |
| 출처 메모 | uspto-grants-2006_10 |