Ethanol → 3-Ethoxy-1-(3-pyridinyl)-2-propen-1-one

HRID 1247954

반응식

HRID 1247954 반응식
CN(C)[CH:3]=[CH:4][C:5]([C:7]1[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=1)=[O:6].C1(C)C=CC(S(O)(=O)=O)=CC=1.[CH2:25]([OH:27])[CH3:26]>>[CH2:25]([O:27][CH:3]=[CH:4][C:5]([C:7]1[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=1)=[O:6])[CH3:26]

참가 물질

4

반응물 3

HCID 702EthanolHCID 6101p-Toluenesulfonic acidHCID 5670331-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one

생성물 1

HCID 540323263-Ethoxy-1-(3-pyridinyl)-2-propen-1-one

실험 절차

A mixture of 0.10 mole of 3-dimethylamino-1-(3-pyridinyl)-2-propen-1-one and 0.20 mole of p-toluenesulfonic acid in 150 ml of anhydrous ethanol was refluxed for 10 hours. The solvent was removed and the residue partitioned between water and dichloromethane. The organic layer was dried over magnesium sulfate and the solvent removed, giving 3-ethoxy-1-(3-pyridinyl)-2-propen-1-one.

후처리

  1. temperaturewas refluxed for 10 hours
  2. customThe solvent was removed
  3. customthe residue partitioned between water and dichloromethane
  4. dry with materialThe organic layer was dried over magnesium sulfate
  5. customthe solvent removed

출처 및 근거

ORD 기록
ord-64c5b816faa34d3e82a72f8bd2cc1385
출처 데이터셋
uspto-grants-1985_06
특허 번호
US04521422

연결된 노트

불러오는 중…