S-Benzoyl-3-mercapto-2-methylpropanoyl chloride → N-(3-benzoylthio-2(R)-methylpropionyl)-N-(2-indanyl)glycine

HRID 1248061

반응식

HRID 1248061 반응식
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[NH:10][CH2:11][C:12]([OH:14])=[O:13].[C:15]([S:23][CH2:24][C@@H:25]([CH3:29])[C:26](Cl)=[O:27])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:15]([S:23][CH2:24][C@H:25]([CH3:29])[C:26]([N:10]([CH:2]1[CH2:3][C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH2:1]1)[CH2:11][C:12]([OH:14])=[O:13])=[O:27])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

3

반응물 2

HCID 194598S-Benzoyl-3-mercapto-2-methylpropanoyl chlorideHCID 99901132-Indanylglycine

생성물 1

HCID 13472315N-(3-benzoylthio-2(R)-methylpropionyl)-N-(2-indanyl)glycine

실험 절차

By reacting N-(2-indanyl)glycine with 3-benzoylthio-2(R)-methylpropionyl chloride in a similar manner to that of Example 37, there is obtained N-(3-benzoylthio-2(R)-methylpropionyl)-N-(2-indanyl)glycine as colorless needles.

출처 및 근거

ORD 기록
ord-2fe0d7b4e0964c8698f3defa9dfb8586
출처 데이터셋
uspto-grants-1985_06
특허 번호
US04521607

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