Ammonia → 2-Amino-4-(3-chloropropyl)-6-trichloromethyl-1,3,5-triazine
반응식
[Cl:1][CH2:2][CH2:3][CH2:4][C:5]1[N:10]=[C:9]([C:11]([Cl:14])([Cl:13])[Cl:12])[N:8]=[C:7](C(Cl)(Cl)Cl)[N:6]=1.[NH3:19].O>O1CCCC1>[NH2:19][C:7]1[N:6]=[C:5]([CH2:4][CH2:3][CH2:2][Cl:1])[N:10]=[C:9]([C:11]([Cl:12])([Cl:13])[Cl:14])[N:8]=1참가 물질
5
실험 절차
102.3 g of 2-(3-chloro-n-propyl)-4,6-bis-(trichloromethyl)-1,3,5-triazine are dissolved in 100 ml of tetrahydrofuran, and to this solution are added at room temperature, with stirring, 400 ml of concentrated aqueous ammonia solution. After 30 minutes, 500 ml of water are addded, and the reaction mixture is extracted twice with 100 ml of ether each time. The ether phases are dried over magnesium sulfate, filtered, and concentrated by evaporation to leave 68.3 g of title product in the form of light-brown oil.
후처리
- additionto this solution are added at room temperature
- extractionthe reaction mixture is extracted twice with 100 ml of ether each time
- dry with materialThe ether phases are dried over magnesium sulfate
- filtrationfiltered
- concentrationconcentrated by evaporation
출처 및 근거
- ORD 기록
- ord-f347435542864956b4aaf97785a07137
- 출처 데이터셋
- uspto-grants-1985_06
- 특허 번호
- US04523947
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