Potassium Carbonate → HCID 2817949, 화합물

HRID 1248543노트

반응식

HRID 1248543 반응식
[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1.C([O-])([O-])=O.[K+].[K+].Br[CH:24]([CH3:29])[C:25]([O:27][CH3:28])=[O:26]>CC(C)=O>[Cl:1][C:2]1[C:3]([O:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH:24]([CH3:29])[C:25]([O:27][CH3:28])=[O:26])=[CH:12][CH:11]=2)=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 95576Methyl 2-bromopropionateHCID 6208804-(3,5-Dichloro-pyridin-2-yloxy)-phenol

생성물 1

HCID 2817949HCID 2817949, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

The above phenol (1.3 g, 5.08 mm), K2CO3 (1.05 g), methyl α-bromopropionate (0.85 ml, 1.5 eq) and acetone (20 ml) is refluxed for 8 hours. The mixture is then filtered and the filtrate concentrated to give oily methyl 2-[4-(3,5-dichloro-2-pyridyloxy)phenoxy]propionate.

후처리

  1. filtrationThe mixture is then filtered
  2. concentrationthe filtrate concentrated

출처 및 근거

ORD 기록
ord-d13411615cff46aa9a23b16d7b39d414
출처 데이터셋
uspto-grants-1985_06
특허 번호
US04525205

반응 노트

불러오는 중…