Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Saccharin → 4-trifluoroacetoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Saccharin | HCID 5143 | — |
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Trifluoromethanesulfonic acid | HCID 62406 | — |
| 반응물 | 4-hydroxy-1H-1,2-benzisothiazole-1,1,3(2H)-trione | HCID 1486522 | — |
| 생성물 | 4-trifluoroacetoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide | HCID 54372980 | — |
반응 단계
The specification describes a process for preparing 4-hydroxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide, a sweetener, from 1,2-benzisothiazol-3(2H)-one-1,1-dioxide by anodic oxidation in the presence of trifluoroacetic acid or trifluoromethanesulfonic acid and, optionally, in the presence of salts which increase the conductivity. The oxidation is effected in an anhydrous medium and the 4-trifluoroacetoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide formed as an intermediate when, for example, trifluoroacetic acid is used is decomposed with water to obtain the desired end product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04626325 |
| 출처 데이터셋 | uspto-grants-1986_12 |
| ORD ID | ord-aa6994a49181462785998d04c8f4aa4f |
| 출처 메모 | uspto-grants-1986_12 |