Potassium Iodide → HCID 13090791, 화합물
반응식
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[C:7]([Cl:12])[C:6]=2[CH2:13]Cl.[C-]#N.[K+].[I-].[K+].[CH3:20][N:21](C)C=O>O>[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[C:7]([Cl:12])[C:6]=2[CH2:13][C:20]#[N:21]참가 물질
6
실험 절차
49 parts of 3,7-dichloro-8-chloromethylquinoline (Example 1), 13 parts of potassium cyanide and 0.1 part of potassium iodide in 300 parts of dimethylformamide were heated at 150° C. for 4 hours. Water was added to the reaction solution and the precipitated product was filtered off with suction and recrystallized from methylglycol. 32 parts of 3,7-dichloro-8-cyanomethylquinoline of melting point 152° C. were obtained. The yield corresponds to 67% of theory.
후처리
- filtrationthe precipitated product was filtered off with suction
- customrecrystallized from methylglycol
출처 및 근거
- ORD 기록
- ord-6939bbb304e9499786a930eff7a46c22
- 출처 데이터셋
- uspto-grants-1986_12
- 특허 번호
- US04632696
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