HCID 53962035, 화합물 → methyl 4-chloro-1H-indole-2-carboxylate

HRID 1249927노트

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HRID 1249927 반응식
[N:1]([C:4](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[Cl:16])[C:5]([O:7][CH3:8])=[O:6])=[N+]=[N-]>C1(C)C=CC=CC=1>[CH3:8][O:7][C:5]([C:4]1[NH:1][C:15]2[C:10]([CH:9]=1)=[C:11]([Cl:16])[CH:12]=[CH:13][CH:14]=2)=[O:6]

참가 물질

3

반응물 1

HCID 53962035HCID 53962035, 화합물

생성물 1

HCID 4714974methyl 4-chloro-1H-indole-2-carboxylate

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Methyl 2-azido-3-(2-chlorophenyl)-propenoate (3.566 g, 144 mmol) was suspended in toluene (800 ml) and the mixture was heated at reflux for three hours, then cooled and allowed to stir at room temperature overnight. A yellow crystalline material was obtained by filtration and recrystallised from hexane.

후처리

  1. temperaturethe mixture was heated
  2. temperatureat reflux for three hours
  3. temperaturecooled
  4. customA yellow crystalline material was obtained by filtration
  5. customrecrystallised from hexane

출처 및 근거

ORD 기록
ord-9fbec446f6ef4eada94f1b9e25d08cbe
출처 데이터셋
uspto-grants-2002_01
특허 번호
US06335360B1

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