Oxalyl chloride → HCID 22609552, 화합물

HRID 1250955노트

반응식

HRID 1250955 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:13]=[CH:14]/[CH:15]=[CH:16]/[C:17]([OH:19])=O)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].C(Cl)(=O)C([Cl:23])=O>CN(C)C=O.C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:13]=[CH:14]/[CH:15]=[CH:16]/[C:17]([Cl:23])=[O:19])[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10]

참가 물질

4

반응물 2

HCID 65578Oxalyl chlorideHCID 15257506HCID 15257506, 화합물

생성물 1

HCID 22609552HCID 22609552, 화합물

시약·촉매·용매 1

HCID 22350042dichloromethane N,N-dimethylformamide용매

실험 절차

A solution of 185 mg (0.70 mmol) of 5-(3,4,5-trimethoxyphenyl)penta-(2E,4E)-dienoic acid in anhydrous dimethylformamide-methylene chloride (0.2 ml-2 ml) was cooled in an ice bath. To the solution was added 0.10 ml (1.1 mmol) of oxalyl chloride with stirring. The ice bath was removed, and the mixture was stirred for 30 minutes at room temperature. The reaction mixture was concentrated under reduced pressure to obtain crude crystals of 5-(3,4,5-trimethoxyphenyl)penta-(2E,4E)-dienoyl chloride.

후처리

  1. customThe ice bath was removed
  2. stirringthe mixture was stirred for 30 minutes at room temperature
  3. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-ffdbbd77bd1a489e87a4fcb0164bc570
출처 데이터셋
uspto-grants-2002_01
특허 번호
US06340682B1

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