참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Bromotoluene | HCID 7805 | — |
| 반응물 | Triisopropyl borate | HCID 21531 | — |
| 반응물 | Lithium phenylacetylide | HCID 3437284 | — |
| 촉매 | HCID 178418397 | HCID 178418397 | — |
| 용매 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 용매 | Tetrahydrofuran dimethoxyethane | HCID 22732251 | — |
| 생성물 | Benzene, 1-methyl-4-(phenylethynyl)- | HCID 3014187 | — |
반응 단계
General Procedure A. To a solution of lithium phenylacetylide (15.2 ml, 15.2 mmol) in DME (20 ml) under Argon at −78° C. was added triisopropoxylborane (3.5 ml, 15.2 mmol). The mixture was stirred at −78° C. for 1.5 hours. A solution of 1-bromo-4-methylbenzene (2 g, 11.7 mmol) in DME/THF (10 ml/10 ml) was degassed with dry argon, Pd(PPh3)4 (405 mg, 0.35 mmol) was added and the solution was degassed for another 5 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07728014B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_06 |
|---|
| ORD ID | ord-ec8adad63d0041a0969484598bc2e2fd |
|---|
| 출처 메모 | uspto-grants-2010_06 |
|---|
