Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 5,6-diphenyl-1,2,4-triazine-3-carboxylate → Ethyl 5,6-diphenylpyridine-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 5,6-diphenyl-1,2,4-triazine-3-carboxylate | HCID 317903 | — |
| 반응물 | N-Vinylpyrrolidine | HCID 3014294 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Ethyl 5,6-diphenylpyridine-2-carboxylate | HCID 14789610 | — |
반응 단계
General Procedure D. Ethyl 5,6-diphenyl-1,2,4-triazine-3-carboxylate (Compound 11, 200 mg, 0.66 mmol) and crude 1-vinylpyrrolidine (Compound 38, 2 g) in CHCl3 (20 ml) was heated at 75° C. overnight under nitrogen. The solvent was removed in vacuo, and the residue was purified by silica gel column chromatography (20% ethyl acetate in hexane) to yield the title compound as a light yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728014B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-407ba34a62634895800105f14ad97f06 |
| 출처 메모 | uspto-grants-2010_06 |