Ethanolamine → HCID 14209234, 화합물

HRID 1252397노트

반응식

HRID 1252397 반응식
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1Cl)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH2:13]([CH2:15][NH2:16])[OH:14]>O>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH:16][CH2:15][CH2:13][OH:14])=[CH:9][CH:8]=[CH:7][CH:6]=2

참가 물질

4

반응물 2

HCID 700EthanolamineHCID 6183063-Bromo-4-chloroquinoline

생성물 1

HCID 14209234HCID 14209234, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
150 °C

실험 절차

A mixture of 9.1 g of 3-bromo-4-chloro-quinoline and 2.0 g of ethanolamine was heated at 150° C. for 30 minutes. The reaction mixture was cooled, 60 ml of water was added and the precipitate was collected by filtration and recrystallized from isopropanol. The yield was 9.5 g, mp 163°-165° C.

후처리

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe precipitate was collected by filtration
  3. customrecrystallized from isopropanol

출처 및 근거

ORD 기록
ord-3b0008b4baf14a619161af1e78ef9f03
출처 데이터셋
uspto-grants-1988_05
특허 번호
US04743601

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