Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dicyclohexylcarbodiimide → HCID 54399293, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 2-(Dimethoxyphosphoryl)acetic acid | HCID 189964 | — |
| 반응물 | Methyl 4-aminopyridine-2-carboxylate | HCID 3759117 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 54399293 | HCID 54399293 | — |
반응 단계
A mixture of 1.0 g of methyl 4-aminopicolinate, 1.0 g of α-(dimethylphosphono)-acetic acid and 1.0 g of dicyclohexylcarbodiimide in 10 ml of methylene chloride is stirred at room temperature for 6 hours. After filtration and removal of solvent the residue is chromatographed on silica gel with 5% methanol/methylene chloride as the eluent to afford methyl 4-(α-dimethylphosphonoacetamido)-picolinate as a viscous oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04746653 |
| 출처 데이터셋 | uspto-grants-1988_05 |
| ORD ID | ord-a2a22c313bd44465a2801eae875476c0 |
| 출처 메모 | uspto-grants-1988_05 |