Chloride → L-Proline, ethyl ester

HRID 1253494

반응식

HRID 1253494 반응식
[NH:1]1[CH2:8][CH2:7][CH2:6][C@H:2]1[C:3]([OH:5])=[O:4].[Cl-].[CH3:10][CH2:11]O>>[NH:1]1[CH2:8][CH2:7][CH2:6][C@H:2]1[C:3]([O:5][CH2:10][CH3:11])=[O:4]

참가 물질

4

반응물 3

HCID 312ChlorideHCID 702EthanolHCID 145742L-Proline

생성물 1

HCID 79888L-Proline, ethyl ester

반응 조건

온도
70 °C

실험 절차

Into a 500 ml 3-necked roundbottom flask, was placed a solution of proline (20.0 g, 174. mmol) in EtOH (100 ml). To the above was added thinyl chloride (40 ml). The resulting solution was heated to 70° C., with stirring, for 12 hours. The mixture was concentrated by evaporation. To afford ethyl prolinate that was used without further purification.

후처리

  1. customInto a 500 ml 3-necked roundbottom flask, was placed
  2. concentrationThe mixture was concentrated by evaporation

출처 및 근거

ORD 기록
ord-3e0e149d45424cc48db96ba50c681e26
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08455477B2

연결된 노트

불러오는 중…