HCID 178471941, 화합물 → Ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate

반응식

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3](/[N:7]=[CH:8]/[CH:9]([C:15]([O:17]CC)=O)[C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:2]=1>O(C1C=CC=CC=1)C1C=CC=CC=1>[OH:17][CH:15]1[C:2]2[C:3](=[CH:4][CH:5]=[CH:6][N:1]=2)[N:7]=[CH:8][CH:9]1[C:10]([O:12][CH2:13][CH3:14])=[O:11]

참가 물질

반응 조건

온도: 250 °C

실험 절차

Diethyl [(E)-(pyridin-3-ylimino)methyl]malonate (9 g, 34 mmol) was dissolved in 1,1′-oxydibenzene (150 ml). The mixture was heated at 250° C. for 2 hours, and then cooled to room temperature. The reaction mixture was filtered to give ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate.

후처리

temperaturecooled to room temperature
filtrationThe reaction mixture was filtered

출처 및 근거

ORD 기록: ord-c8cab84f26644dd2b6cbc67822f071e7
출처 데이터셋: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08455477B2

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참가 물질

반응물 1

HCID 178471941HCID 178471941, 화합물

생성물 1

HCID 67207071Ethyl 4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylate

시약·촉매·용매 1

HCID 7583Diphenyl Ether용매

반응 조건

온도: 250 °C

실험 절차

후처리

temperaturecooled to room temperature
filtrationThe reaction mixture was filtered

출처 및 근거

ORD 기록: ord-c8cab84f26644dd2b6cbc67822f071e7
출처 데이터셋: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08455477B2

반응 노트

불러오는 중…