HCID 67207576, 화합물 → HCID 178516432, 화합물
반응식
[OH:1][CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][N:10]=2)[N:5]=[CH:4][CH:3]1C(O)=O>N1C2C(=CC=CC=2)C=CC=1>[N:5]1[C:6]2[C:11](=[N:10][CH:9]=[CH:8][CH:7]=2)[C:2]([OH:1])=[CH:3][CH:4]=1참가 물질
3
반응 조건
- 온도
- 200 °C
실험 절차
4-hydroxy-3,4-dihydro-1,5-naphthyridine-3-carboxylic acid (1.4 g, 7.3 mmol) was dissolved in quinoline (50 ml). The mixture was heated to 200° C. for 2 hours, and then cooled to room temperature. The reaction mixture was filtered to give 1,5-naphthyridin-4-ol.
후처리
- temperaturecooled to room temperature
- filtrationThe reaction mixture was filtered
출처 및 근거
- ORD 기록
- ord-497e9de9f69e4ddc8c67e21cfc4a87f9
- 출처 데이터셋
- uspto-grants-2013_06
- 특허 번호
- US08455477B2
반응 노트
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