Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminopropylphosphonic acid → (3-(((6-Phenyl-5-(p-tolyl)pyridin-2-yl)methyl)amino)propyl)phosphonic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminopropylphosphonic acid | HCID 97587 | — |
| 반응물 | Sodium cyanoborohydride | HCID 5003444 | — |
| 반응물 | 6-Phenyl-5-p-tolylpyridine-2-carbaldehyde | HCID 86619072 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (3-(((6-Phenyl-5-(p-tolyl)pyridin-2-yl)methyl)amino)propyl)phosphonic acid | HCID 44234515 | — |
반응 단계
Following General Procedure M, 6-phenyl-5-p-tolylpyridine-2-carbaldehyde (Compound 55, 67 mg, 0.25 mmol), (3-aminopropyl)-phosphonic acid (34 mg, 0.25 mmol), Bu4NOH (0.2 ml, 0.25 mmol, 1 M in MeOH) and NaCNBH3 (15 mg, 0.25 mmol) in MeOH (3 ml) were reacted to produce the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728014B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-022616730b0b4007b11ba681d49f496b |
| 출처 메모 | uspto-grants-2010_06 |