Hexahydro-1H-furo[3,4-c]pyrrole → 1-(6-(Dihydro-1H-furo[3,4-c]pyrrol-5(3H,6H,6aH)-yl)quinolin-4-yl)-3-(pyrazin-2-yl)urea

HRID 1254818노트

반응식

HRID 1254818 반응식
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][O:2]1.Br[C:10]1[CH:11]=[C:12]2[C:17](=[CH:18][CH:19]=1)[N:16]=[CH:15][CH:14]=[C:13]2[NH:20][C:21]([NH:23][C:24]1[CH:29]=[N:28][CH:27]=[CH:26][N:25]=1)=[O:22]>>[CH2:1]1[CH:5]2[CH2:6][N:7]([C:10]3[CH:11]=[C:12]4[C:17](=[CH:18][CH:19]=3)[N:16]=[CH:15][CH:14]=[C:13]4[NH:20][C:21]([NH:23][C:24]3[CH:29]=[N:28][CH:27]=[CH:26][N:25]=3)=[O:22])[CH2:8][CH:4]2[CH2:3][O:2]1

참가 물질

3

반응물 2

HCID 21421150Hexahydro-1H-furo[3,4-c]pyrroleHCID 248590151-(6-Bromoquinolin-4-yl)-3-(pyrazin-2-yl)urea

생성물 1

HCID 442477531-(6-(Dihydro-1H-furo[3,4-c]pyrrol-5(3H,6H,6aH)-yl)quinolin-4-yl)-3-(pyrazin-2-yl)urea

실험 절차

The compound was prepared by the method described for Example 1 using hexahydro-furo[3,4-c]pyrrole and 1-(6-bromoquinolin-4-yl)-3-(pyrazin-2-yl)urea as starting compounds.

후처리

  1. customThe compound was prepared by the method

출처 및 근거

ORD 기록
ord-c510e8b0535b47bd87d4416262267bd5
출처 데이터셋
uspto-grants-2013_06
특허 번호
US08455648B2

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