Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminopropylphosphonic acid → (3-{[3-(4-Ethylphenyl)-[2,4']-bipyridin-6-ylmethyl]-amino}-propyl)-phosphonic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminopropylphosphonic acid | HCID 97587 | — |
| 반응물 | Sodium cyanoborohydride | HCID 5003444 | — |
| 반응물 | 3-(4-Ethylphenyl)-[2,4']-bipyridinyl-6-carbaldehyde | HCID 86619073 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (3-{[3-(4-Ethylphenyl)-[2,4']-bipyridin-6-ylmethyl]-amino}-propyl)-phosphonic Acid | HCID 44217417 | — |
반응 단계
Following General Procedure M, 3-(4-ethyl-phenyl)-[2,4′]-bipyridinyl-6-carbaldehyde (Compound 58, 50 mg, 0.17 mmol), (3-amino-propyl)-phosphonic acid (24 mg, 0.17 mmol), Bu4NOH (0.17 ml, 0.17 mmol, 1 M in MeOH) and NaCNBH3 (11 mg, 0.17 mmol) in MeOH (3 ml) were reacted to produce the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728014B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c102a456f8734650b93e4a7c443cdb74 |
| 출처 메모 | uspto-grants-2010_06 |