Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminopropylphosphonic acid → 3-((6-Phenyl-5-(4-propylphenyl)pyridin-2-yl)methylamino)propylphosphonic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminopropylphosphonic acid | HCID 97587 | — |
| 반응물 | Sodium cyanoborohydride | HCID 5003444 | — |
| 반응물 | 6-Phenyl-5-(4-propylphenyl)pyridine-2-carbaldehyde | HCID 86619075 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-((6-Phenyl-5-(4-propylphenyl)pyridin-2-yl)methylamino)propylphosphonic Acid | HCID 49787250 | — |
반응 단계
Following General Procedure M, 6-phenyl-5-(4-propylphenyl)pyridine-2-carbaldehyde (Compound 59, 74 mg, 0.25 mmol), (3-amino-propyl)phosphonic acid (34 mg, 0.25 mmol), Bu4NOH (0.25 ml, 0.25 mmol, 1M in MeOH) and NaCNBH3 (15 mg, 0.25 mmol) in MeOH (5 ml) were reacted to produce the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728014B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-7379c5469345430caa35630f18548b1c |
| 출처 메모 | uspto-grants-2010_06 |